An objectionable, despicable person.
“My mother never saw the irony in calling me a son of a bitch.” — attributed to various people, such as Jack Nicholson and Richard Jeni
Any objectionable thing.
"This son of a bitch won’t move!" Marty exclaimed as he grappled with the supermarket cart.
Used to express anger, contempt, astonishment, disappointment etc.